Modafinil stimulate the central nervous system but are not as habit-forming or as dangerous as older stimulants such as methylphenidate and amphetamine.

What is Narcolepsy?

A neurologic (nervous system) sleep disorder, narcolepsy causes people to feel excessively sleepy during the day and may cause them to fall asleep suddenly. These episodes of sleepiness and loss of control over muscle movement can make driving, working or participating in activities dangerous.

There is no cure for narcolepsy, but medications can reduce symptoms and help you manage your day-to-day activities more effectively. It is important to discuss your treatment goals with your healthcare team to determine the best approach for you.

Medications used to treat narcolepsy include central nervous system stimulants, like modafinil australia online, and sodium oxybate, which can help you stay awake by improving your brain’s ability to regulate your sleep-wake cycle. It is not known exactly how modafinil works to improve wakefulness, but it may involve mimicking the effects of adrenaline in your brain or increasing dopamine activity. It is only available with a prescription and should be taken as directed by your doctor.

Narcolepsy Symptoms

People with narcolepsy often experience extreme sleepiness throughout the day, which can cause problems at school and work. The condition can also reduce concentration and make it difficult to drive safely. It can also affect mental health, with those affected by narcolepsy at higher risk of depression and other mental health issues.

Other symptoms include a sudden feeling of falling asleep (microsleeps), which can last for seconds or minutes. People with narcolepsy may have episodes of cataplexy, which is a sudden loss of muscle control that can lead to slurred speech or collapse. They may also experience episodes of automatic behavior, where they continue doing a task even though they are sleeping — for example, driving or writing — but don’t remember what happened.

Narcolepsy is a lifelong disorder, and although it doesn’t cause any permanent damage, it can disrupt many aspects of daily life. It can be hard to keep up with studies or work, and those who have the condition are sometimes misjudged as lazy or rude.

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Narcolepsy Causes

People with narcolepsy often have a genetic mutation that leads to low levels of a brain chemical called hypocretin (hi-poe-KREE-tin). This causes the sleep and wake cycle to get mixed up, and elements of both are present when you're awake. This can lead to problems like slurred speech and memory lapses. It also can cause cataplexy, which is sudden muscle weakness that can range from buckling at the knees to falling to the ground.

Excessive daytime sleepiness can make it hard to concentrate at school or work, and may cause social problems because others don't understand your condition. You can get treatment to improve your quality of life.

A few people with narcolepsy have sleep attacks, which are periods of uncontrollable falling asleep or waking up. These can last a few seconds to a few minutes and are triggered by strong emotions such as anger or surprise. They can be dangerous if they happen while driving or doing another task that puts you at risk of injury, such as cooking or swimming.

Narcolepsy Treatments

Many people with narcolepsy benefit from a combination of medications and lifestyle changes. Some examples include sticking to a sleep schedule, eating smaller meals more often and avoiding caffeine or smoking. Exercise and emotional support also may be helpful.

Healthcare providers often prescribe medicine that stimulates the central nervous system to help prevent excessive sleepiness. Commonly prescribed stimulants include modafinil, armodafinil and methylphenidate. Older stimulant medicines, like clonazepam (Klonopin) and dexamphetamine (Adderall XR, Dexedrine, Desoxyn) are not as effective and can be habit-forming. Solriamfetol and pitolisant are two newer medicines that can also be used to treat cataplexy and hypnagogic hallucinations.

Some narcolepsy treatments work by improving the way your brain uses orexin, a chemical that helps regulate how awake and alert you feel. Researchers are investigating other medications that add more orexin to the brain or make it work better. These treatments may one day reduce narcolepsy symptoms and improve quality of life.